Degrees and Appointments 

• Ph.D. 1985, University of Texas, Austin

Specialties: Biophysics, Metabolism, Signaling, and Regulation, Protein and Membrane Biochemistry, Structural Biology

Research and Publications

Research Description

My group determines the atomic structures of proteins and seeks to understand how protein structure gives rise to protein function – both in vitro and in living cells. The problems we study have at their heart a fundamental structure-function question, but also address questions of importance to human health. Our approaches include X-ray crystallography, rapid kinetic measurements, spectroscopy, theory, protein expression, drug discovery, molecular genetics and related techniques.