Degrees and Appointments
- Ph.D. 1985, University of Texas, Austin
Specialties: Biophysics, Metabolism, Signaling, and Regulation, Protein and Membrane Biochemistry, Structural Biology
My group determines the atomic structures of proteins and seeks to understand how protein structure gives rise to protein function – both in vitro and in living cells. The problems we study have at their heart a fundamental structure-function question, but also address questions of importance to human health. Our approaches include X-ray crystallography, rapid kinetic measurements, spectroscopy, theory, protein expression, drug discovery, molecular genetics and related techniques.