CBC Colloquium: Platelet Mechanobiology - Shear, Membranes, Fluidity and Stiffness! “Opportunities for Novel Biochemical Strategies to Improve Cardiovascular Health”Thursday, September 30, 2021 - 3:30pm
Abstract - In this seminar I will present new mechanisms and the latest understanding of platelet activation. Why is this important? Cardiovascular therapeutic devices (CTDs) – e.g. ventricular assist devices, total artificial heart, percutaneous heart valves, and stents - are life-saving therapeutics increasingly utilized in the US and worldwide. Despite CTD efficacy they remain plagued by thrombosis, leading to device malfunction, embolic events, and death.