Degrees and Appointments
- B.A. 1997, University of Iowa
- Ph.D. 2005, University of Iowa
- Postdoctoral Fellow 2005-2011, Duke University
- Assistant to Associate Professor, 2011-2017, The Ohio State University
- Associate Professor, 2017-present, University of Arizona
Specialties: Metabolism, Signaling, and Regulation Protein and Membrane Biochemistry
My research focuses on understanding how transforming growth factor beta (TGF-beta) signaling controls a wide spectrum of molecular and cellular effects ranging from proliferation to differentiation and cell motility. While gene regulation is the primary mode of signal transduction, often occurring in a highly context-specific manner, our long-term goals include characterizing novel mechanisms by which the canonical effectors, namely the nuclear shuttling SMAD transcription factors and TGF-beta-activated kinase 1 (TAK1), directly modulate cellular activities.